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- ...of natural opioids (such as opium or heroin). Synthetic opioids, like all opioids, can reduce feelings of pain, can produce feelings of euphoria, relaxation Some synthetic opioids have medical uses, fentanyl is sometimes used to treat pain associated with10 KB (1,609 words) - 15:22, 23 April 2017
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- ...lling between the brain and body. It belongs to a group of drugs known as 'opioids' that are from the opium poppy. It is prescribed for the control of chronic ...l's analgesic activity is, most likely, due to its conversion to morphine. Opioids close N-type voltage-operated calcium channels (OP2-receptor agonist) and o27 KB (3,939 words) - 15:26, 23 April 2017
- * [[Synthetic opioids|Synthetic opioids]]882 bytes (76 words) - 11:43, 4 April 2017
- ...ine overdose is rarely fatal unless the drugs are mixed with barbiturates, opioids, alcohol, or tricyclic antidepressants. ...g benzodiazepines by themselves or in combination with other drugs such as opioids and alcohol were being reported as early as the 1970's, though a lack of co40 KB (5,758 words) - 15:05, 23 April 2017
- ...oblematic use and drug-related crime, predominantly among those also using opioids. Due to the often chaotic nature of users' lives, it is likely that drug su ...toxication and consume larger doses than they otherwise would. Cocaine and opioids is a particularly dangerous combination because cocaine has a short half-li75 KB (11,796 words) - 15:06, 23 April 2017
- ...however, there are countries, where significant numbers of users of other opioids exist, for example Finland (buprenorphine) or Estonia ([[*Fentanyl|Fentanyl ...ct <ref name="16a">'''Heroin''', 2017, http://www.drugscience.org.uk/drugs/opioids/heroin/</ref>.83 KB (13,146 words) - 15:13, 23 April 2017
- ...include 1,4-butanediol, 2-methyl-2-butanol, benzodiazepines, GHB, GBL, and opioids <ref name="12a"/>. * '''opioids''' - Both substances bring a risk of vomiting and unconsciousness. If the u52 KB (8,176 words) - 15:14, 23 April 2017
- * '''Opioids''' - Stimulants increase respiration rate allowing a higher dose of opiates29 KB (4,611 words) - 15:15, 23 April 2017
- ...s to control withdrawal symptoms and cravings caused by addiction to other opioids or to other addictive substances such as alcohol. There is no scientific ev ...in and opioid withdrawal but structurally it is not the same as the common opioids morphine or codeine. Animal studies suggest that the primary mitragynine ph27 KB (3,918 words) - 15:15, 23 April 2017
- ...n the brain as a biological regulator. It has analgesic effects similar to opioids in nature, as well as anaesthetic and anxiolytic actions. Its anxiolytic ef * '''Opioids''' - Both substances potentiate the ataxia and sedation caused by the other24 KB (3,870 words) - 10:47, 7 June 2017
- ...s the principal source of most naturally occurring opioid receptor agonist opioids. The Poppy straw is the dried mature plant except the seeds, which is also ...mitant use of tramadol increases the seizure risk in patients taking other opioids. These agents are often individually epileptogenic and may have additive ef27 KB (4,206 words) - 15:19, 23 April 2017
- ...include 1,4-butanediol, 2-methyl-2-butanol, benzodiazepines, GHB, GBL, and opioids <ref name="7a"/>.32 KB (4,774 words) - 15:20, 23 April 2017
- |* [[:Category:Opioids]] |* [[Synthetic opioids]]3 KB (267 words) - 13:59, 7 July 2018
- ...2-methyl-2-butanol, barbiturates, benzodiazepines, GHB/GBL, methaqualone, opioids, phenothiazines <ref name="13a"/>) - This combination can result in dangero92 KB (14,429 words) - 15:23, 23 April 2017
- ...of natural opioids (such as opium or heroin). Synthetic opioids, like all opioids, can reduce feelings of pain, can produce feelings of euphoria, relaxation Some synthetic opioids have medical uses, fentanyl is sometimes used to treat pain associated with10 KB (1,609 words) - 15:22, 23 April 2017
- ...endorphin (which reduces anxiety) and enhances the action of serotonin and opioids (which causes sedation) <ref name="9a"/>.66 KB (10,234 words) - 15:24, 23 April 2017
- ...binding, analgesic and antitussive potency of tramadol and other selected opioids''', ''Arzneimittel-Forschung'', 1988, 38, 7, 877-880, https://www.ncbi.nlm. ...n the body and also work upon the μ-opioid receptor set. The way in which opioids structurally mimic these natural endorphins results in their euphoria, pain23 KB (3,238 words) - 15:27, 23 April 2017
- <!-- | Opioids | Tramadol, tapentadol[1], pethidine, fentanyl, pentazocine, bupren | Opioids6 KB (624 words) - 15:29, 23 April 2017
- [[Category:Opioids]] ...n the body and also work with the μ-opioid receptor set. The way in which opioids structurally mimic these natural endorphins results in their euphoria, pain13 KB (1,951 words) - 15:22, 23 April 2017
- ...r or strong cravings associated with other more common depressants such as opioids, alcohol or benzodiazepines.12 KB (1,611 words) - 15:26, 23 April 2017
- ...anediol, 2-methyl-2-butanol, alcohol, barbiturates, GHB/GBL, methaqualone, opioids) - This combination can result in dangerous or even fatal levels of respira * '''Opioids''' - Central nervous system and/or respiratory-depressant effects may be ad22 KB (3,100 words) - 15:27, 23 April 2017
- ...anediol, 2-methyl-2-butanol, alcohol, barbiturates, GHB/GBL, methaqualone, opioids) - This combination can result in dangerous or even fatal levels of respira * '''opioids''' - Central nervous system and/or respiratory-depressant effects may be ad27 KB (3,876 words) - 09:43, 25 April 2017
- [[Category:Opioids]][[Category:Depressants]][[Category:Analgesics]][[Category:Sedatives]] ...s include heroine. Codeine, however, is much milder than many of the other opioids. The drug's intent is to alleviate moderate to severe pain due to outpatien38 KB (5,612 words) - 08:41, 25 April 2017
- Tolerance develops with continued use of many substances like alcohol, opioids, and benzodiazepines like diazepam. Over time, as the body adapts to the me * '''[[Opioids]]''' - [[Central nervous system]] and/or respiratory-depressant effects may17 KB (2,316 words) - 14:36, 28 April 2017
- [[Category:Opioids]][[Category:Analgesics]] ...y suppression and pain relief effects appear to stem from the way in which opioids mimic endogenous endorphins. Endorphins are responsible for [[analgesia]],18 KB (2,428 words) - 10:05, 2 May 2017
- [[Category:Opioids]][[Category:Analgesics]] ...the μ-opioid receptor as an agonist. This occurs due to the way in which opioids structurally mimic [[endogenous]] endorphins. Endorphins are responsible fo20 KB (2,761 words) - 15:52, 3 May 2017
- [[Category:Opioids]] [[Endogenous]] opioids include endorphins, enkephalins and dynorphins. Morphine appears to mimic a27 KB (3,839 words) - 10:44, 7 May 2017
- ...o inhibit the release of vasopressin, somatostatin, insulin, and glucagon. Opioids close N-type voltage-operated calcium channels (kappa-receptor agonist) and * harm related to pre-existing conditions for which opioids may be contra-indicated <ref name="1098a">Nielsen, S., '''Oxycodone''', Nat21 KB (2,942 words) - 21:20, 8 May 2017
- ...-methyl-2-butanol, [[alcohol]], barbiturates, [[GBL / GHB]], methaqualone, opioids) - This combination can result in dangerous or even fatal levels of respira16 KB (2,242 words) - 16:00, 9 May 2017
- ...iol, 2-methyl-2-butanol, [[alcohol]], barbiturates, GHB/GBL, methaqualone, opioids) - This combination can result in dangerous or even fatal levels of [[respi ...in mixing 'Z drugs' with alcohol or other [[CNS]] depressants, such as the opioids.19 KB (2,748 words) - 14:51, 10 May 2017
- [[Category:Opioids]] ...ibed to people wanting to come off these drugs. It is different from other opioids in that it is a partial opioid agonist. This means that there is less eupho18 KB (2,467 words) - 07:24, 12 May 2017
- ...ef name="0112a">'''Methadone''', 2016, http://www.drugscience.org.uk/drugs/opioids/methadone/</ref>. ...is a prescription drug, and is part of a group of drugs known as opioids. Opioids are depressant drugs, which means they slow down the messages travelling be59 KB (8,773 words) - 20:37, 16 May 2017
- Naltrexone reverses the effects of opioids and is used as a relapse prevention tool. It is not a maintenance treatment ...ccupy the relevant receptor sites in the brain, it reverses the effects of opioids among dependent individuals. Naltrexone Hydrochloride is a non-addictive su14 KB (2,017 words) - 12:34, 18 May 2017
- ...g this they displace and over time replace the indigenous endorphins. Some opioids stimulate the receptors (agonists), some occupy and block action at the rec ...receptors in the brain than do other opioids, making it more difficult for opioids to act at the relevant sites when buprenorphine is in the system. Interesti12 KB (1,670 words) - 14:47, 18 May 2017
- ...barbiturates, or general anaesthetics) and does not reverse the effects of opioids <ref name="1171a"/>.7 KB (946 words) - 15:51, 19 May 2017
- [[Category:Opioids]] [[Category:Opiate antagonists]] Naloxone is a drug that reverses the effects of opioids among dependent individuals <ref name="1177a">'''Naloxone''', 2017, http://11 KB (1,507 words) - 11:56, 20 May 2017
- ...move them into it. Examples include benzodiazepines, [[GBL / GHB]], 2M2B, opioids, and most commonly, [[alcohol]]. * '''Opioids''' - [[CNS]] depression, difficult breathing, heart issues, hepatoxic, just23 KB (3,121 words) - 20:17, 26 May 2017
- ...move them into it. Examples include benzodiazepines, [[GBL / GHB]], 2M2B, opioids, and most commonly, [[alcohol]]. * '''Opioids''' - This combination can potentiate the effects of the opioid.19 KB (2,704 words) - 10:25, 30 May 2017
- * '''Opioids''' - Central nervous system and/or respiratory-depressant effects may be ad9 KB (1,301 words) - 14:10, 5 June 2017
- * '''Opioids''' - Central nervous system and/or respiratory-depressant effects may be ad10 KB (1,415 words) - 09:17, 7 June 2017
- ...entanil''', 2018, https://castlecraig.co.uk/resources/drugs/types-of-drugs/opioids-painkillers/carfentanil/</ref>. ...eptors as an agonist. It will induce similar effects of analgesia as other opioids, however, due to its potency, it will also induce strong side effects such12 KB (1,837 words) - 15:19, 6 July 2018